Q- Which one of the following defines the drug efficacy?
A- The capacity a drug to affect a condition irrespective of the dose
B- The dose of a drug needed to produce a maximal effect
C- The impact of the drug on a wide range of patients
D- The minimal amount of drug administered that leads to toxicity
Q- Which one of the following indicates drug resistance?
A- Altered effect of the drug when used with another drug
B- Induction of liver metabolism
C- No or minimum effect on a microorganism due to genetic mutation
D- Response to a drug decreases after repeated use
Q- Which one of the following drugs is most likely to cause severe bone marrow depression?
A- Cyclosporine
B- Prednisone
C- Sirolimus
D- Tacrolimus