Q- Stimulation of hepatic microsomal cytochrome P450 enzymes can cause which one of the following?
A- Decreased metabolism of certain drugs
B- Enhancement of excretion of some drugs
C- Increased intestinal absorption of certain drugs
D- Increased metabolism of certain drugs
D- Increased metabolism of certain drugs- Induction of hepatic cytochrome P450 enzymes leads to increased drug metabolism, which can reduce the effectiveness of drugs that are metabolized by these pathways. It does not decrease metabolism, increase intestinal absorption, or directly enhance excretion.
Q- Which of the following conditions is an indication for interferon gamma?
A- Chronic granulomatous disease
B- Chronic myeloblastic leukemia
C- Hepatitis A
D- Glomerulonephritis
A- Chronic granulomatous disease- Interferon-gamma is used to boost macrophage function and is specifically indicated for Chronic Granulomatous Disease (CGD) to reduce the frequency of severe infections. It is not used for CML, hepatitis A, or glomerulonephritis.
Q- Which one of the following is a fat-soluble vitamin?
A- Ascorbic acid
B- Retinoid
C- Riboflavin
D- Thiamine
B- Retinoid- Retinoids (Vitamin A) are fat-soluble vitamins. Ascorbic acid (Vitamin C), Riboflavin (B2), and Thiamine (B1) are all water-soluble vitamins.
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