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Repeated USMLE Questions Step 1- 355



Q- Which of the following statements correctly describes the volume of distribution of a drug?

A- It is a kinetic parameter that correlates dose with plasma level of a drug at zero time

B- It is the capacity of a drug to attach to plasma protein

C- It is the concentration of the drug in plasma at a certain time

D- It is the rate of diffusion of the drug through intracellular component

A- It is a kinetic parameter that correlates dose with plasma level of a drug at zero time



Q- Deficiency of which of the following enzymes is associated with von Gierke’s disease?

A- α-1,4-phosphorylase

B- Glucose-6-phosphatase

C- Hexosaminidase A

D- Phosphofructokinase-1

B- Glucose-6-phosphatase



Q- Which of the following differentiates HIV virus from RNA tumor viruses?

A- HIV virus contains 2 copies of RNA

B- HIV virus contains the pol gene

C- HIV virus has a cytolytic activity

D- HIV virus is a retrovirus

C- HIV virus has a cytolytic activity



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