Repeated USMLE Questions Step 1- 376

Dr Ray Makar

3 years ago

5f6f99a86d5042e04c4180a5aa10b8a51510435721_cropped | Repeated USMLE Questions

Q- An old woman is having difficulty in holding or keeping her head up. She also mentions that she experiences fatigue in her hands shortly after washing dishes. Physical examination reveals neck flexion weakness as well as proximal weakness in the arms. Which of the following is the initial diagnosis for her condition?

A- Meningitis

B- Myasthenia gravis

C- Peripheral neuropathy

D- Spinal cord compression

B- Myasthenia gravis- It is one of the most common autoimmune diseases that affect the neuromuscular junction. It is typically characterized by painless, fatigable muscle weakness. It has a bimodal age of onset, meaning it will either affect at a young age or elderly.

Q- A 30-year-old pregnant woman visits her obstetrician’s clinic at 10 weeks gestation. The patient has a history of type 1 diabetes and is worried that her condition may cause some complications in her pregnancy. From the list below, advise your patient that all of the following are a potential risk of type 1 diabetes in pregnancy EXCEPT which one?

A- Fetal malformations

B- Having to undergo a cesarean section

C- Preterm labor

D- Spontaneous abortions in the first trimester

B- Having to undergo a cesarean section- Diabetes is known to cause complications in pregnancies. Type 1 diabetes puts a pregnant woman at risk for preterm labor, preeclampsia, spontaneous abortions, and even fetal malformations due to fetal growth restrictions. There is, however, no reason to believe that if she has type 1 diabetes, she will have to undergo a cesarean section. A normal delivery is also possible, but the obstetrician will be the best person to recommend which type of birth plan is best suited for her and the baby.

Q- Which one of the following medications inhibits HMG-CoA reductase?

A- Aspirin

B- Digoxin

C- Simvastatin

D- Tacrolimus

C- Simvastatin

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