Repeated USMLE Questions Step 1- Review- 26



Q- Which one of the following drugs blocks the urinary excretion of penicillin which leads to prolonged high serum concentration?

A- Chloramphenicol

B- Cimetidine

C- Probenecid

D- Rifampicin

C- Probenecid- It delays the tubular secretion of penicillin resulting in high serum concentration for a long period of time.



Q- Elevation of which one of the following substances in blood occurs due to reduced renal blood flow?

A- Ammonia

B- Calcium

C- Cholesterol

D- Renin

D- Renin- It is secreted by the juxtaglomerular cells as result of reduced renal blood flow. It results in elevated blood pressure which in turn elevates renal blood flow.



Q- Which of the following groups of drugs are useful for night terrors and sleepwalking?

A- Alcohols

B- Barbiturates

C- Benzodiazepines

D- Tricyclic anti-depressants

C- Benzodiazepines- This group of drugs are associated with reduced REM and delta sleep.



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