Free Questions and Answers for All Medical Students all over the World
Q- A 27-year-old woman presents with a painless thyroid nodule. Biopsy shows tumor cells forming follicles but without the nuclear features of papillary carcinoma. Capsular invasion is present. What is the most likely diagnosis? A- Anaplastic thyroid carcinoma B- Follicular thyroid carcinoma C- Medullary thyroid carcinoma D- Papillary thyroid carcinoma Q- A 50-year-old man … Read more
Q- A 34-year-old woman presents with chronic diarrhea and abdominal pain. Colonoscopy reveals transmural inflammation with skip lesions. Which complication is most likely in this condition? A- Toxic megacolon B- Colorectal adenocarcinoma C- Fistula formation D- Primary sclerosing cholangitis Q- A 58-year-old man presents with fatigue and easy bruising. Peripheral smear shows blasts with … Read more
Q- A 45-year-old woman presents with episodic headaches, sweating, and palpitations. Imaging reveals an adrenal medullary tumor. Which histologic pattern is most characteristic of this tumor? A- Keratin pearls B- Psammoma bodies C- Sheets of small blue cells D- Zellballen pattern Q- A 63-year-old man with long-standing diabetes presents with progressive renal failure. Renal … Read more
Q- A 2-year-old child has recurrent infections with catalase-positive organisms. Neutrophils show absent oxidative burst on flow cytometry. Which enzyme is defective? A- Adenosine deaminase B- Glucose-6-phosphate dehydrogenase C- NADPH oxidase D- Myeloperoxidase Q- A patient has difficulty rising from a chair and climbing stairs. Biopsy shows endomysial inflammation and CD8+ T-cell infiltration. Which … Read more
Q- A patient with chronic kidney disease develops secondary hyperparathyroidism. Which of the following biochemical changes directly stimulates parathyroid hormone (PTH) secretion in this condition? A- Decreased 1,25-dihydroxyvitamin D levels B- Decreased serum phosphate C- Increased calcium-sensing receptor activation D- Increased intestinal calcium absorption Q- A mutation prevents phosphorylation of the regulatory light chain … Read more
Q- A 59-year-old man presents with progressive dysphagia. Endoscopy reveals an ulcerated mass in the distal esophagus. Biopsy shows malignant gland-forming cells. Which risk factor is most strongly associated with this condition? A- Alcohol consumption B- Chronic gastroesophageal reflux disease C- Human papillomavirus infection D- Iron deficiency anemia Q- A 66-year-old woman presents with … Read more