Repeated USMLE Questions Step 1 Review-174- Pathology

Q- A 64-year-old man with a long history of smoking presents with hematuria. Cystoscopy reveals a papillary tumor arising from the bladder mucosa. Which molecular alteration is most commonly associated with low-grade papillary urothelial carcinoma? A- KRAS mutation B- FGFR3 mutation C- BRAF mutation D- APC mutation   Q- A 14-year-old boy presents with a … Read more

Repeated USMLE Questions Step 2 CK- Review- 60

Q- A 28-year-old woman presents with palpitations and tremor. ECG shows atrial fibrillation. Labs reveal suppressed TSH and elevated T4. What is the most appropriate initial treatment? A- Methimazole B- Propranolol C- Radioactive iodine therapy D- Thyroidectomy   Q- A 35-year-old man presents with fever, hypotension, and a diffuse rash after a minor surgical procedure. … Read more

Repeated USMLE Questions Step 1 Review-173- Pharmacology

Q- A patient with Parkinson’s disease is treated with selegiline. What is the primary mechanism of this drug? A- Inhibition of catechol-O-methyltransferase B- Inhibition of monoamine oxidase B C- Stimulation of dopamine receptors D- Stimulation of muscarinic receptors   Q- A patient treated with verapamil develops constipation and bradycardia. What class of drug does verapamil … Read more

Repeated USMLE Questions Step 1- Review-172

Q- A child has chronic diarrhea and failure to thrive. Stool is positive for fat. The sweat chloride test is elevated. Which mechanism explains the GI symptoms? A- Decreased pancreatic enzyme secretion B- Increased bile acid synthesis C- Increased gastric acid production D- Increased intestinal chloride secretion   Q- A patient has progressive weakness and … Read more

Repeated USMLE Questions Step 2 CK- Review- 59

Q- A 63-year-old woman with diabetes presents with fever, flank pain, and dysuria. CT scan shows gas within the renal parenchyma. What is the most likely diagnosis? A- Acute pyelonephritis B- Emphysematous pyelonephritis C- Renal abscess D- Xanthogranulomatous pyelonephritis   Q- A 74-year-old woman presents with acute onset right-sided weakness and slurred speech that began … Read more

Repeated USMLE Questions Step 1 Review-171- Pharmacology

Q- A patient treated with a nonselective beta blocker develops hypoglycemia that is difficult to recognize. What explains the masking of hypoglycemia symptoms? A- Alpha receptor blockade B- Beta-1 receptor stimulation C- Beta-2 receptor blockade D- Muscarinic receptor blockade   Q- A patient with hyperlipidemia is treated with cholestyramine. What is the primary mechanism by … Read more