Repeated USMLE Questions Step 1- Review-182

Q- Which one of the following classes of drugs decreases preload by increasing venous capacitance? A- ACE inhibitors B- Beta blockers C- Nitrates D- Thiazide diuretics   Q- A patient with vitamin B12 deficiency develops neurological symptoms. Which metabolic change is responsible? A- Increased homocysteine only B- Increased methylmalonic acid only C- Increased homocysteine and … Read more

Repeated USMLE Questions Step 2 CK- Review- 64

Q- A 62-year-old man presents with fever, dyspnea, urinary frequency, and perineal pain. Digital rectal examination reveals a tender, boggy prostate. Which of the following is the most appropriate next step in management? A- Begin empiric antibiotics B- Perform prostate massage for culture C- Schedule transurethral resection of the prostate D- Treat with an alpha-blocker … Read more

Repeated USMLE Questions Step 1 Review-181- Pharmacology

Q– A patient with heart failure is prescribed a drug that inhibits the Na⁺/K⁺-ATPase pump, increasing intracellular calcium in cardiac myocytes. Which one of the following drugs is most likely responsible? A- Amiodarone B- Digoxin C- Diltiazem D- Verapamil Correct Answer B- Digoxin- Digoxin inhibits the Na⁺/K⁺-ATPase pump, increasing intracellular sodium. This reduces Na⁺/Ca²⁺ exchange, … Read more

Repeated USMLE Questions Step 1- Review-180

Q- A patient is prescribed heparin. Which one of the following laboratory tests is used to monitor its effectiveness? A- Bleeding time B- International normalized ratio (INR) C- Platelet count D- Partial thromboplastin time (PTT)   Q- Which one of the following types of lung cancer could be accompanied by Horner’s syndrome? A- Adenocarcinoma of … Read more

Repeated USMLE Questions Step 2 CK- Review- 63

Q- A 40-year-old man presents with severe hypertension, palpitations, headaches, and diaphoresis. CT scan reveals an adrenal mass. What is the best preoperative management? A- Beta-blocker before alpha-blocker B- Immediate surgery without medications C- Intravenous nitroglycerin only D- Phenoxybenzamine before the beta-blocker   Q- A 52-year-old woman presents with progressive fatigue and pruritus. Labs show … Read more

Repeated USMLE Questions Step 1 Review-179- Pharmacology

Q- A patient treated with amoxicillin develops a rash after taking the medication. What type of reaction is most likely? A- Type I hypersensitivity B- Type II hypersensitivity C- Type III hypersensitivity D- Type IV hypersensitivity   Q- A patient taking NSAIDs develops decreased kidney function. What is the mechanism of this effect? A- Decreased … Read more