Repeated USMLE Questions Step 2 CK- Review- 61

Q- A 59-year-old man presents with crushing chest pain for 1 hour. ECG shows ST elevation in the anterior leads. The hospital does not have a catheterization laboratory, and transfer would take 3 hours. What is the most appropriate next step? A- Administer fibrinolytic therapy B- Begin aspirin therapy only C- Start intravenous heparin and … Read more

Repeated USMLE Questions Step 1 Review-175- Pharmacology

Q- A patient with atrial fibrillation is treated with dofetilide. Which electrophysiologic effect explains the antiarrhythmic action of this drug? A- Decreased phase 0 depolarization B- Increased refractory period by potassium channel blockade C- Inhibition of calcium influx in AV node D- Sodium channel blockade during depolarization   Q- A patient treated with acetazolamide develops … Read more

Repeated USMLE Questions Step 1 Review-174- Pathology

Q- A 64-year-old man with a long history of smoking presents with hematuria. Cystoscopy reveals a papillary tumor arising from the bladder mucosa. Which molecular alteration is most commonly associated with low-grade papillary urothelial carcinoma? A- KRAS mutation B- FGFR3 mutation C- BRAF mutation D- APC mutation   Q- A 14-year-old boy presents with a … Read more

Repeated USMLE Questions Step 2 CK- Review- 60

Q- A 28-year-old woman presents with palpitations and tremor. ECG shows atrial fibrillation. Labs reveal suppressed TSH and elevated T4. What is the most appropriate initial treatment? A- Methimazole B- Propranolol C- Radioactive iodine therapy D- Thyroidectomy   Q- A 35-year-old man presents with fever, hypotension, and a diffuse rash after a minor surgical procedure. … Read more

Repeated USMLE Questions Step 1 Review-173- Pharmacology

Q- A patient with Parkinson’s disease is treated with selegiline. What is the primary mechanism of this drug? A- Inhibition of catechol-O-methyltransferase B- Inhibition of monoamine oxidase B C- Stimulation of dopamine receptors D- Stimulation of muscarinic receptors   Q- A patient treated with verapamil develops constipation and bradycardia. What class of drug does verapamil … Read more

Repeated USMLE Questions Step 1- Review-172

Q- A child has chronic diarrhea and failure to thrive. Stool is positive for fat. The sweat chloride test is elevated. Which mechanism explains the GI symptoms? A- Decreased pancreatic enzyme secretion B- Increased bile acid synthesis C- Increased gastric acid production D- Increased intestinal chloride secretion   Q- A patient has progressive weakness and … Read more