Repeated USMLE Questions Step 2 CK- Review- 62

Q- A 68-year-old man presents with fever, productive cough, and confusion. Blood pressure is 82/50 mmHg despite receiving 2 liters of IV fluids. What is the next best step in management? A- Administer intravenous norepinephrine B- Begin oral antibiotics C- Obtain chest CT scan D- Start furosemide   Q- A 73-year-old man presents with urinary … Read more

Repeated USMLE Questions Step 1 Review-177- Pharmacology

Q- A patient treated with tacrolimus after kidney transplantation develops nephrotoxicity. What is the primary molecular mechanism of tacrolimus? A- Blocks IL-2 transcription by inhibiting calcineurin B- Inhibits dihydrofolate reductase C- Inhibits inosine monophosphate dehydrogenase D- Stimulates T-cell apoptosis directly   Q- A patient with chronic angina is treated with ranolazine. What is the primary … Read more

Repeated USMLE Questions Step 1- Review-176

Q- A drug that increases GABA activity in the central nervous system is prescribed for anxiety. Which class of drugs acts by increasing the frequency of chloride channel opening at the GABA-A receptor? A- Barbiturates B- Benzodiazepines C- Selective serotonin reuptake inhibitors D- Tricyclic antidepressants   Q- A woman has heavy menstrual bleeding and prolonged … Read more

Repeated USMLE Questions Step 2 CK- Review- 61

Q- A 59-year-old man presents with crushing chest pain for 1 hour. ECG shows ST elevation in the anterior leads. The hospital does not have a catheterization laboratory, and transfer would take 3 hours. What is the most appropriate next step? A- Administer fibrinolytic therapy B- Begin aspirin therapy only C- Start intravenous heparin and … Read more

Repeated USMLE Questions Step 1 Review-175- Pharmacology

Q- A patient with atrial fibrillation is treated with dofetilide. Which electrophysiologic effect explains the antiarrhythmic action of this drug? A- Decreased phase 0 depolarization B- Increased refractory period by potassium channel blockade C- Inhibition of calcium influx in AV node D- Sodium channel blockade during depolarization   Q- A patient treated with acetazolamide develops … Read more

Repeated USMLE Questions Step 1 Review-174- Pathology

Q- A 64-year-old man with a long history of smoking presents with hematuria. Cystoscopy reveals a papillary tumor arising from the bladder mucosa. Which molecular alteration is most commonly associated with low-grade papillary urothelial carcinoma? A- KRAS mutation B- FGFR3 mutation C- BRAF mutation D- APC mutation   Q- A 14-year-old boy presents with a … Read more