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USMLE Internal Medicine Questions

Internal medicine is the largest part of USMLE Step 2 CK. These questions focus on what the exam really tests: the next best step in diagnosis and management.

High-yield internal medicine topics
• Cardiology – STEMI management, heart failure, arrhythmias and aortic dissection.
• Infectious disease – sepsis, pneumonia, MSSA bacteremia and C. difficile.
• Gastroenterology – variceal bleeding, pancreatitis, primary biliary cholangitis and mesenteric ischemia.
• Hematology – TTP, warfarin reversal and antiphospholipid syndrome.
• Endocrinology – thyroid disease, pheochromocytoma and Cushing syndrome.

Try each question before opening the answer, then read the explanation even when you get it right. Each post has 3–8 exam-style questions with answers and short explanations written by Dr. Ray Makar.

Want hundreds more? See the Repeated USMLE Questions eBook series on Amazon.

USMLE Step 2 CK Questions: Acute Prostatitis, MSSA Bacteremia & Ischemic Colitis (Review 64)

by Dr Ray Makar

Step 2 CK practice questions with answers: managing acute bacterial prostatitis, the best antibiotic for MSSA bacteremia, and ischemic colitis after aortic aneurysm repair.

Categories USMLE Internal Medicine Questions, USMLE Step 2 CK Tags Gastroenterology, Infectious Diseases, internal medicine, urology Leave a comment

USMLE Step 2 CK Questions: Pheochromocytoma, Primary Biliary Cholangitis & Testicular Torsion (Review 63)

by Dr Ray Makar

Step 2 CK practice questions with answers: alpha blockade before surgery for pheochromocytoma, treating primary biliary cholangitis, and testicular torsion.

Categories USMLE Internal Medicine Questions, USMLE Step 2 CK Tags Endocrinology, Gastroenterology, internal medicine, urology Leave a comment

USMLE Step 2 CK Questions: Septic Shock, Urinary Retention & Ovarian Torsion (Review 62)

by Dr Ray Makar

Step 2 CK practice questions with answers: vasopressors in septic shock, postoperative urinary retention, and emergency management of ovarian torsion.

Categories USMLE Internal Medicine Questions, USMLE Step 2 CK Tags Infectious Diseases, internal medicine, Obstetrics and Gynecology, urology Leave a comment

USMLE Step 2 CK Questions: STEMI Fibrinolysis, Spontaneous Bacterial Peritonitis & Migraine (Review 61)

by Dr Ray Makar

Step 2 CK practice questions with answers: when to give fibrinolytics in STEMI, treating spontaneous bacterial peritonitis, and first-line therapy for acute migraine.

Categories USMLE Internal Medicine Questions, USMLE Step 2 CK Tags Cardiology, Gastroenterology, internal medicine, Neurology Leave a comment

USMLE Step 2 CK Questions: Thyrotoxic Atrial Fibrillation, Toxic Shock Syndrome & Dysphagia (Review 60)

by Dr Ray Makar

Step 2 CK practice questions with answers: beta blockers for hyperthyroid atrial fibrillation, toxic shock syndrome, and the workup of progressive dysphagia.

Categories USMLE Internal Medicine Questions, USMLE Step 2 CK Tags Endocrinology, Gastroenterology, Infectious Diseases, internal medicine Leave a comment

USMLE Step 2 CK Questions: Emphysematous Pyelonephritis, Stroke Thrombolysis & Gallstone Pancreatitis (Review 59)

by Dr Ray Makar

Step 2 CK practice questions with answers: emphysematous pyelonephritis in diabetes, blood pressure before stroke thrombolysis, and cholecystectomy timing in gallstone pancreatitis.

Categories USMLE Internal Medicine Questions, USMLE Step 2 CK Tags Gastroenterology, internal medicine, Nephrology, Neurology Leave a comment
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Recent Posts

  • USMLE Step 1 Questions: Nitrates, Vitamin B12 Deficiency & Mitochondrial Inheritance (Review 182)
  • USMLE Step 2 CK Questions: Acute Prostatitis, MSSA Bacteremia & Ischemic Colitis (Review 64)
  • USMLE Step 1 Questions: Heparin Monitoring, Pancoast Tumor & Megaloblastic Anemia (Review 180)
  • USMLE Step 2 CK Questions: Pheochromocytoma, Primary Biliary Cholangitis & Testicular Torsion (Review 63)
  • USMLE Step 2 CK Questions: Septic Shock, Urinary Retention & Ovarian Torsion (Review 62)


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