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USMLE Internal Medicine Questions

Internal medicine is the largest part of USMLE Step 2 CK. These questions focus on what the exam really tests: the next best step in diagnosis and management.

High-yield internal medicine topics
• Cardiology – STEMI management, heart failure, arrhythmias and aortic dissection.
• Infectious disease – sepsis, pneumonia, MSSA bacteremia and C. difficile.
• Gastroenterology – variceal bleeding, pancreatitis, primary biliary cholangitis and mesenteric ischemia.
• Hematology – TTP, warfarin reversal and antiphospholipid syndrome.
• Endocrinology – thyroid disease, pheochromocytoma and Cushing syndrome.

Try each question before opening the answer, then read the explanation even when you get it right. Each post has 3–8 exam-style questions with answers and short explanations written by Dr. Ray Makar.

Want hundreds more? See the Repeated USMLE Questions eBook series on Amazon.

USMLE Step 2 CK Questions: Primary Biliary Cholangitis, Massive Pulmonary Embolism & Mononucleosis (Review 58)

by Dr Ray Makar

Step 2 CK practice questions with answers: treating primary biliary cholangitis, thrombolysis for massive pulmonary embolism, and sports advice in infectious mononucleosis.

Categories USMLE Internal Medicine Questions, USMLE Step 2 CK Tags Gastroenterology, Infectious Diseases, internal medicine, Pulmonology Leave a comment

USMLE Step 2 CK Questions: C. difficile, Acute Mesenteric Ischemia & Right Ventricular MI (Review 57)

by Dr Ray Makar

Step 2 CK practice questions with answers: oral vancomycin for C. difficile, CT angiography in mesenteric ischemia, and IV fluids for right ventricular infarction.

Categories USMLE Internal Medicine Questions, USMLE Step 2 CK Tags Cardiology, Gastroenterology, Infectious Diseases, internal medicine 3 Comments

USMLE Step 2 CK Questions: Preeclampsia, Advance Directives & Anastomotic Leak (Review 56)

by Dr Ray Makar

Step 2 CK practice questions with answers: magnesium sulfate and delivery in preeclampsia, honoring an advance directive, and anastomotic leak after surgery.

Categories USMLE Internal Medicine Questions, USMLE Step 2 CK Tags ethics, Obstetrics and Gynecology, surgery Leave a comment

USMLE Step 2 CK Questions: Acute Pancreatitis, TTP, Warfarin Reversal & Guillain-Barré (Review 55)

by Dr Ray Makar

Five Step 2 CK questions with answers: severe acute pancreatitis, plasma exchange for TTP, warfarin reversal, tubo-ovarian abscess, and IVIG for Guillain-Barré syndrome.

Categories USMLE Internal Medicine Questions, USMLE Step 2 CK Tags Gastroenterology, Hematology, internal medicine, Neurology, Obstetrics and Gynecology Leave a comment

USMLE Step 2 CK Questions: HFpEF, Dermatomyositis, Pancreatic Cancer & Antiphospholipid Syndrome (Review 54)

by Dr Ray Makar

Five Step 2 CK questions with answers: heart failure with preserved ejection fraction, dermatomyositis and malignancy, azithromycin QT prolongation, Courvoisier sign, and antiphospholipid syndrome.

Categories USMLE Internal Medicine Questions, USMLE Step 2 CK Tags Cardiology, Hematology, internal medicine, oncology Leave a comment

USMLE Step 2 CK Questions: Aortic Stenosis, PID, Malignant Hyperthermia & Ménière Disease (Review 53)

by Dr Ray Makar

Five Step 2 CK questions with answers: aortic stenosis murmur, treating pelvic inflammatory disease, malignant hyperthermia, Ménière disease, and hemolytic anemia.

Categories USMLE Internal Medicine Questions, USMLE Step 2 CK Tags Cardiology, Hematology, internal medicine, Obstetrics and Gynecology, surgery Leave a comment
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Recent Posts

  • USMLE Step 1 Questions: Nitrates, Vitamin B12 Deficiency & Mitochondrial Inheritance (Review 182)
  • USMLE Step 2 CK Questions: Acute Prostatitis, MSSA Bacteremia & Ischemic Colitis (Review 64)
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  • USMLE Step 2 CK Questions: Pheochromocytoma, Primary Biliary Cholangitis & Testicular Torsion (Review 63)
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