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Immunology

Immunology is tested heavily on USMLE Step 1. This page collects every immunology practice question on the site, including questions from mixed review sets.

High-yield immunology topics
• Immunodeficiencies: CGD, Wiskott-Aldrich and Chédiak-Higashi
• Leukocyte adhesion deficiency
• Hypersensitivity reactions
• Transplant immunosuppressants: tacrolimus and mycophenolate
• Autoantibodies in Graves disease and myasthenia gravis

Try each question before opening the answer, then read the explanation even when you get it right. Each post has 3–8 exam-style questions with answers and short explanations written by Dr. Ray Makar.

Want hundreds more? See the Repeated USMLE Questions eBook series on Amazon.

USMLE Step 1 Questions: Cystic Fibrosis, Myasthenia Gravis & Pheochromocytoma (Review 172)

by Dr Ray Makar

Step 1 practice questions with answers: pancreatic insufficiency in cystic fibrosis, the thymus in myasthenia gravis, and the neural crest origin of pheochromocytoma.

Categories USMLE Step 1 Tags Endocrinology, genetics, Immunology, pathology Leave a comment

USMLE Step 1 Questions: Chronic Granulomatous Disease, Graves Disease, Alport Syndrome & More (Review 162)

by Dr Ray Makar

Five Step 1 questions with answers: NADPH oxidase in chronic granulomatous disease, polymyositis, Graves disease antibodies, Alport syndrome, and omeprazole.

Categories USMLE Step 1 Tags Endocrinology, Immunology, Nephrology, pathology, pharmacology Leave a comment

USMLE Step 1 Questions: Vitamin D in CKD, Smooth Muscle, TAP Transporter & Enzyme Kinetics (Review 160)

by Dr Ray Makar

Five Step 1 questions with answers: vitamin D in chronic kidney disease, smooth muscle contraction, TAP transporter defects, irreversible enzyme inhibitors, and oxidative phosphorylation.

Categories USMLE Step 1 Tags Biochemistry, Immunology, Nephrology, physiology Leave a comment

USMLE Step 1 Questions: Leukocyte Adhesion Deficiency, Thiamine, 21-Hydroxylase & G Proteins (Review 156)

by Dr Ray Makar

Five Step 1 questions with answers: CD18 and leukocyte adhesion, thiamine deficiency enzymes, use-dependent sodium channel blockers, 21-hydroxylase deficiency, and G protein signaling.

Categories USMLE Step 1 Tags Biochemistry, Endocrinology, Immunology, pharmacology, physiology Leave a comment

USMLE Step 1 Questions: Wiskott-Aldrich Syndrome, Patent Ductus Arteriosus & Graves Disease (Review 147)

by Dr Ray Makar

Step 1 practice questions with answers: the WASP gene in Wiskott-Aldrich syndrome, the continuous murmur of patent ductus arteriosus, and Graves disease antibodies.

Categories USMLE Step 1 Tags Cardiology, Endocrinology, genetics, Immunology Leave a comment

USMLE Step 1 Questions: Buprenorphine, Hyaline Arteriosclerosis & Chédiak-Higashi Syndrome (Review 145)

by Dr Ray Makar

Step 1 practice questions with answers: buprenorphine as a partial opioid agonist, hyaline arteriosclerosis in hypertension, and phagolysosome defects in Chédiak-Higashi syndrome.

Categories USMLE Step 1 Tags Immunology, pathology, pharmacology Leave a comment
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