A 46 year-old man underwent a kidney transplantation last week due to chronic renal failure. The surgery was successful and the transplanted kidney started to produce urine during the operation. Today, his urine examination shows high creatinine and low urinary output. He has no pain or fever. A biopsy taken from the transplanted kidney shows cellular infiltrate .
Which of these cells is responsible for this patient’s recent condition?
A- B Lymphocytes
B- Cytotoxic T cells
C- Fibrocytes
D- Plasma cells
E- T-helper cells
Answer:
This is a case of acute rejection of kidney transplant. It is caused by a T cell–mediated delayed hypersensitivity reaction to allograft histocompatibility antigens.
The correct answer is B
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