Q- Which one of the following autoantibodies is associated with Goodpasture syndrome?
A- Anti-Ach receptor
B- Anti-basement membrane
C- Anti-centromere
D- Anti-histone
B- Anti-basement membrane- Goodpasture syndrome is characterized by anti–glomerular basement membrane (anti-GBM) antibodies, which attack the basement membranes of the kidneys and lungs.
Q- Deficiency of which of the following enzymes most likely result in the development of Cori disease?
A- Debranching enzyme (alpha-1,6-glucoside)
B- Glucose-6-phosphatase
C- Lysosomal alpha-1,4 glucosidase
D- Muscle glycogen phosphorylase
A- Debranching enzyme (alpha-1,6-glucoside)- Cori disease (Glycogen Storage Disease type III) is caused by a deficiency of the debranching enzyme, leading to accumulation of abnormal glycogen and hypoglycemia. The other enzyme deficiencies correspond to different glycogen storage diseases.
Q- Which of the following indicates the probability that a person who has a positive test result has the disease?
A- Attributable risk
B- Positive predictive value
C- Sensitivity
D- Specificity
B- Positive predictive value- Positive predictive value (PPV) tells you the probability that a person with a positive test result actually has the disease. Sensitivity and specificity describe test characteristics, and attributable risk is an epidemiologic measure unrelated to diagnostic testing.
Thank you so much Dr. Inam. I appreciate your feedback.
Tnx sir from your struggle to do for us