Pharmacology MCQs- 256

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Q- Which of the following is the mechanism of action of cromolyn for asthmatic patients?

A- Blocks adenosine receptors in bronchial smooth muscle

B- Inhibits COX 2

C- Inhibits phosphodiesterase

D- Prevents degradation of mast cells

D- Prevents degranulation of mast cells- Cromolyn is a mast cell stabilizer. It prevents mast cells from degranulating, thereby reducing the release of histamine and other inflammatory mediators in asthma. It does not block adenosine receptors, inhibit COX-2, or inhibit phosphodiesterase.



Q- Which of the following receptors are membrane receptors (not intracellular)?

A- Receptors for steroids

B- Receptors for thyroid hormones

C- Receptors for vitamin D

D- The nicotinic receptors for acetylcholine

D- The nicotinic receptors for acetylcholine- Nicotinic acetylcholine receptors are ligand-gated ion channels located on the cell membrane. Steroid, thyroid hormone, and vitamin D receptors are all intracellular (cytoplasmic or nuclear) receptors.



Q- Which of the following statements correctly describes the lag time of a drug?

A- Time from administration of the drug to appearance in the blood

B- Time from administration of the drug to reaching the minimal effect concentration

C- Time from administration of the drug to reaching the maximal effect concentration.

D- Time in which plasma concentration remains the same

A- Time from administration of the drug to appearance in blood- Lag time is the period between drug administration and the first detectable appearance of the drug in the bloodstream. It does not refer to minimum effect concentration, maximum effect concentration, or a period of constant plasma levels.

 

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