Repeated USMLE Questions Step 1- 362

Q- Which of the following enzymes is markedly elevated in primary biliary cholangitis?

A- Alanine aminotransferase (ALT)

B- Aspartate aminotransferase (AST)

C- Acid phosphatase

D- Alkaline phosphatase

D- Alkaline phosphatase- Primary biliary cholangitis is a chronic autoimmune liver disease characterized by the progressive destruction of intrahepatic bile ducts. The most markedly elevated enzyme in this condition is alkaline phosphatase, which is typically associated with cholestasis.

 

Q- Which of the following is the most likely finding on a biopsy of a case of chronic bronchitis?

A- Abundant mucus with plugging of the bronchioles

B- Caseating granuloma

C- Non-caseating granuloma

D- Interstitial fibrosis

A- Abundant mucus with plugging of the bronchioles- Chronic bronchitis is a lung condition where the airways make too much mucus for a long time. On biopsy, you would see a lot of mucus blocking the bronchioles.  This is what causes the long-term cough and breathing problems.

 

Q- Which of the following is the main role of colchicine in treating acute attack of gout?

A- Decreased uric acid absorption

B- Increased uric acid excretion

C- Inhibition of xanthine oxidase

D- Reduction of gout symptoms and pain

D- Reduction of gout symptoms and pain- Colchicine is used during a gout attack to help relieve pain and swelling, not to lower uric acid levels. It works by reducing inflammation caused by uric acid crystals in the joints. It does not affect uric acid levels directly.

 

More Repeated USMLE Questions Step 1

Check this Review Book for Step 1 

 



4 thoughts on “Repeated USMLE Questions Step 1- 362”

  1. All questions are available at here. Just navigate through it. Thanks Dr. Pasy

  2. Please where can i get the rest of the 362 Repeating questions in USMLE?

  3. I am glad they are helpful. Thank you Dr. Hareem.

  4. Helpful questions

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