Repeated USMLE Questions Step 2 CK- Review- 472

Q- Which one of the following features characterizes Crohn’s disease from ulcerative colitis?

A- Bloody diarrhea

B- Colectomy is curative

C- Continuous disease beginning at the rectum and extending without skipped areas

D- Perineal fissures and fistulas

D- Perineal fissures and fistulas- Crohn’s disease is characterized by transmural inflammation, which often leads to perineal fissures and fistulas. Bloody diarrhea and continuous rectal involvement with curative colectomy are features more typical of ulcerative colitis.



Q- Which of the following is the main site of action of HMG-CoA reductase inhibitors?

A- Blood

B- Liver

C- Kidney

D- GI tract

B- Liver- HMG-CoA reductase inhibitors (statins) act primarily in the liver, where they reduce cholesterol synthesis and upregulate LDL receptors to lower blood LDL levels.



Q- Which of the following management plans is recommended for a case of myocardial infarction with 70% main left stenosis?

A- Coronary artery bypass graft (CABG)

B- Percutaneous coronary intervention (PCI)

C- Percutaneous transluminal coronary angiography (PTCA)

D- Pharmacotherapy and observation

A- Coronary artery bypass graft- A left main coronary artery stenosis of 70% is a high-risk, life-threatening lesion. The recommended management is urgent CABG, which provides better survival compared to PCI for significant left main disease. Pharmacologic therapy alone and PCI/PTCA are inadequate for a lesion of this severity.

 

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Dr Ray Makar

5 thoughts on “Repeated USMLE Questions Step 2 CK- Review- 472”

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