Pathology MCQs- 7 - Repeated USMLE Questions

Q- A 79-year-old woman presents with back pain for 3 months. Radiology of the spines shows compression of T11 and T12 vertebrae. There is no other lesion detected. Which of the following is the most likely diagnosis?

A- Ewing sarcoma

B- Metastatic adenocarcinoma

C- Osteoporosis

D- Osteosarcoma

C- Osteoporosis- It is common in old age and leads to compression fractures of vertebrae.

Q- A 29-year-old woman presents with bloody discharge from her right breast for 3 weeks. There is no pain, fever or swellings. There is no breast mass or lymphadenopathy. Which of the following is the most likely diagnosis?

A- Intraductal papilloma

B- Metastatic carcinoma

C- Pregnancy

D- Prolactinoma

A- Intraductal papilloma- These are localized in the lactiferous tubules behind the nipple and bleeding is the only sign.

Q- A 26-year-old man with a history of HIV infection presents with fatigue and nuchal rigidity for 3 days. Lumber puncture shows increased leukocytes. India ink preparation detects which one of the following organisms?

A- Aspergillus fumigatus

B- Cryptococcus neoformans

C- Streptococcus pneumonia

D- Toxoplasma gondii

B- Cryptococcus neoformans- It is the only one on the list can be seen with India ink preparation.

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