Repeated USMLE Questions Step 1 Review- 140- Pharmacology

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Q- A 60-year-old man with atrial fibrillation is started on amiodarone. Which adverse effect is most commonly associated with this medication?

A- Hyperkalemia

B- Hypoglycemia

C- Nephrotoxicity

D- Pulmonary fibrosis

D- Pulmonary fibrosis- Amiodarone can cause pulmonary fibrosis, thyroid dysfunction, hepatotoxicity, corneal deposits, and skin discoloration (“blue-gray”).

 

Q- A 28-year-old woman develops a dry cough after beginning treatment for hypertension. Which drug is most likely responsible?

A- Amlodipine

B- Lisinopril

C- Losartan

D- Propranolol

B- Lisinopril- ACE inhibitors (like lisinopril) cause a persistent dry cough due to increased bradykinin levels.

 

Q- Which of the following drugs is used as an antidote for acetaminophen overdose?

A- Atropine

B- Flumazenil

C- N-acetylcysteine

D- Naloxone

C- N-acetylcysteine- N-acetylcysteine replenishes glutathione, helping detoxify toxic acetaminophen metabolites.

 

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