Repeated USMLE Questions Step 1- Review- 32

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Q- A 39-year-old woman presents with an inflamed ulcer on the sole of her foot not healed for 2 months. Peripheral sensations are reduced bilaterally. Elevation of which of the following laboratory tests most likely explains this condition?

A- Alanine aminotransferase (ALT)

B- Blood glucose

C -Serum creatinine

D- Urinary sodium

B- Blood glucose- This is a common presentation of type 11 diabetes. Ulcers are common peripherally because of loss of sensations.



Q- A newly born infant is found to have a deformity on the iris. Eye exam reveals keyhole-shaped defect of the iris.

Which of the following terms describes this defect?

A- Aniridia

B- Anisocoria

C- Coloboma

D- Heterochromia iridis

C- Coloboma- It is part of CHARGE syndrome due to CHD7 mutation. Aniridia is absence of the iris, anisocoria is absence of cornea while HI is different colors.



Q- Which one of the following conditions most likely increases the risk for deep venous thrombosis (DVT)?

A- Adenocarcinoma

B- Coronary heart disease

C- Crohn’s disease

D- Pulmonary tuberculosis

A- Adenocarcinoma- Malignancies most likely lead to a hypercoagulable state. Other conditions are less likely to lead to this risk.



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