Repeated USMLE Questions Step 1- Pharmacology- 304

Q- Which one of the following medications enters the cell and acts on a cytoplasmic receptor?

A- Adrenaline

B- Dexamethasone

C- Insulin

D- Propranolol

B-Dexamethasone- It is the only one of the listed medications that combines with a cytoplasmic receptor, enters the nucleus and alters gene expression. Other medications act on membranous receptors.

Q- Which one of the following local anesthetics that causes local vasoconstriction and may leads to hypertension?

A- Cocaine

B- Etidocaine

C- Lidocaine

D- Tetracaine

A-Cocaine- It acts by inhibiting reuptake of norepinephrine through sympathetic nerve endings. Other local anesthetics on the list cause vasodilation.

Q- Which one of the following drugs is the first line medication in transplant immunopharmacology?

A- Cyclosporine

B- Methotrexate

C- Sulfasalazine

D- Thalidomide

A-Cyclosporine- Methotrexate and sulfasalazine are used in the treatment of rheumatoid arthritis and some cancers. Thalidomide is used in erythema nodosum leprosum and multiple myeloma.

Other Pharmacology MCQs

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