Repeated USMLE Questions Step 1- Review- 66

Q- A middle-aged woman presents with trouble vision, amenorrhea and galactorrhea for 4 months. Examination reveals bitemporal hemianopsia. Which of the following tests is most likely beneficial to reach the correct diagnosis?

A- Serum glucose

B- Serum growth hormone

C- Serum prolactin

D- Serum TSH

C- Serum prolactin- This case is most likely pituitary adenoma. Lab will reveal hyperprolactinemia. Imaging will show a large sellar mass.

Q- Which one of the following pathologic findings is most likely seen in the bone marrow biopsy in a patient diagnosed with multiple myeloma?

A- Hypercellularity with many blasts

B- Numerous plasma cells

C- Numerous small mature lymphocytes

D- Reed-Sternberg cells

B- Numerous plasma cells- These appear as lytic bone lesions due to accumulation of plasma cells. Multiple myeloma usually leads to renal failure due to deposition of light chains in the kidneys.

Q- Which one of the following pulmonary abnormalities is a complication of cystic fibrosis?

A- Adenocarcinoma

B- Bronchiectasis

C- Pleural fibrosis

D- Pneumothorax

B- Bronchiectasis- Cystic fibrosis may lead to inflammation and obstruction of bronchi with results in dilation and destruction of these bronchi.

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