Repeated USMLE Questions Step 2 CK- Review- 486

Q- Which one of the following treatments most likely prevents meningeal leukemia in a young boy diagnosed with acute lymphoblastic leukemia?

A- Cyclophosphamide

B- High dose of cortisone

C- Intrathecal methotrexate

D- Radiotherapy

C- Intrathecal methotrexate- Acute lymphoblastic leukemia often causes meningeal leukemia when relapse occurs. Intrathecal methotrexate is the only one on the list prevents meningeal leukemia during if relapse occurs.

Q- An old man presents with acute severe back pain, tachycardia, hypotension and syncope. Which of the following is the most likely diagnosis?

A- Acute mesenteric ischemia

B- Acute myocardial infarction

C- Pulmonary embolism

D- Rupture of abdominal aortic aneurysm

D- Rupture of abdominal aortic aneurysm- This is a typical case. Other conditions have different presentations.

Q- A group of people is assigned for a research study about the effect of a new hypoglycemia medication. Because they are aware of the study, they eat less carbohydrate. Which type of bias is involved in this study?

A- Confounding bias

B- Hawthorne effect

C- Information bias

D- Sample distortion bias

B- Hawthorne effect- This bias will affect the outcome of the study because are aware of it. This bias can be avoided by keeping them unaware of the study. “Blind study”.