Q- A 65-year-old man presents with gradual low back pain increasing in intensity for the last six months. X-ray shows several osteoblastic lesions on lower vertebra and pelvic bones. Additional investigations reveal that those lesions are metastases.
Which of these is most likely the primary cancer in this patient?
A- Chronic lymphocytic leukemia
B- Hodgkin’s lymphoma
C- Prostatic cancer
D- Renal cell carcinoma
E- Thyroid follicular carcinoma
Answer and Explanation
Prostate cancer is the most common cause of osteoblastic metastases, particularly affecting the vertebrae and pelvis. Other cancers, like renal cell carcinoma and thyroid follicular carcinoma, tend to cause osteolytic rather than osteoblastic lesions. Chronic lymphocytic leukemia (CLL) and Hodgkin’s lymphoma do not commonly present with osteoblastic metastases.
The correct answer is C
More Repeated USMLE Questions Step 1
Check this Review Book for Step 1
Study and ques for promotion in the field
Prostate cancer .
c