Q- A patient treated with cisplatin develops hearing loss. What is the mechanism of this adverse effect?
A- Accumulation in cochlear hair cells
B- Autoimmune inner ear inflammation
C- Decreased cerebral perfusion
D- Inhibition of prostaglandin synthesis
Q- A patient taking phenelzine develops severe hypertension after eating aged cheese. What is the underlying cause of this reaction?
A- Excess dopamine release
B- Increased norepinephrine levels
C- Inhibition of acetylcholinesterase
D- Reduced serotonin reuptake
Q- Which medication is most likely to cause photosensitivity as a side effect?
A- Amoxicillin
B- Doxycycline
C- Erythromycin
D- Vancomycin
Q- A patient with heart failure is started on an ACE inhibitor. Which physiologic change contributes to its beneficial effect?
A- Decreased aldosterone secretion
B- Decreased heart rate
C- Increased preload
D- Increased sympathetic tone
Q- A patient with type 2 diabetes is started on acarbose. What is the mechanism of action of this drug?
A- Decreases hepatic gluconeogenesis
B- Delays intestinal carbohydrate absorption
C- Increases insulin secretion
D- Improves insulin sensitivity