Pharmacology MCQs- 257

Q- Which of the following drugs is the most effective treatment for benzodiazepine toxicity?

A- Atropine

B- Dimercaprol

C- Flumazenil

D- Penicillamine

C- Flumazenil- Flumazenil is a benzodiazepine receptor antagonist and is the specific antidote used to reverse benzodiazepine toxicity. The other drugs have no role in treating benzodiazepine overdose.

 

Q- Which of the following correctly describes permissive drug interaction?

A- Decrease in the response of a drug after repeated administration

B- The effect of drug A and drug B is equal to the sum of their individual effects

C- The effect of drug A and drug B is greater than the sum of their individual effects

D- Presence of drug A is required for the full effect of drug B

D- Presence of drug A is required for full effect of drug- A permissive drug interaction occurs when one drug (A) has little or no effect on its own, but its presence is required for another drug (B) to exert its full physiological effect. This is different from additive (B), synergistic (C), or tolerance (A) effects.



Q- Which of the following statements is true about warfarin?

A- Liver is the main site of action of warfarin

B-Toxicity of warfarin is treated by protamine sulfate

C- Warfarin acts by activation of antithrombin

D- Warfarin is monitored by PTT

A- Liver is the main site of action of warfarin- Warfarin works in the liver, where it inhibits vitamin K epoxide reductase, preventing activation of vitamin K–dependent clotting factors (II, VII, IX, X). Protamine sulfate reverses heparin, not warfarin. Warfarin does not activate antithrombin. Monitoring of warfarin is by PT/INR, not PTT.

 

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7 thoughts on “Pharmacology MCQs- 257”

  1. Thank you so much Dr. Muneer. I appreciate your feedback.

  2. warfarin toxicity is treated by vitamin K and FFPs.. heparin toxicity is treated by protamine sulphate.

  3. I am sorry. I don’t have a PDF file for MCQs. Just click on the word “pharmacology” in any question and you will get all pharmacology questions. Thank you

  4. Pls I want PDF file MCQ of pharmacology

  5. I am sorry. I don’t have a PDF file but I if you click on the word: “pharmacology”, you will find all questions related to pharmacology.

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  7. I must say the answer for warfarin query is that toxicity of warfarin is treated by protamine sulphate is true

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