Q- Which one of the following medications inhibits protein synthesis by binding to 50S subunit and preventing the formation of the initiation complex?
A- Azithromycin
B- Clindamycin
C- Linezolid
D- Minocycline
C- Linezolid- Linezolid inhibits protein synthesis by binding to the 50S ribosomal subunit and blocking formation of the initiation complex. Azithromycin and clindamycin also bind the 50S subunit but work by different mechanisms, and minocycline binds the 30S subunit.
Q- Which of the following substances is used in mercury poisoning?
A- Flumazenil
B- Fomepizole
C- Methylene blue
D- Succimer
D- Succimer- Succimer (DMSA) is a chelating agent used in cases of heavy metal poisoning, including mercury. Flumazenil reverses benzodiazepines, fomepizole treats methanol and ethylene glycol toxicity, and methylene blue treats methemoglobinemia.
Q- Which of the following conditions could be a serious side effect of sumatriptan?
A- Coronary vasospasm
B- Cutaneous flushing
C- Dilated cardiomyopathy
D- Torsades de pointes
A- Coronary vasospasm- Sumatriptan is a serotonin (5-HT1B/1D) agonist that can cause coronary vasospasm, which may lead to chest pain or myocardial ischemia. The other conditions are not characteristic complications of sumatriptan.
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