Repeated USMLE Questions Step 1 | Review

Q- Which one of the following conditions is characterized by the detection of atrophied villi on an intestinal biopsy?

A- Celiac disease

B- Crohn’s disease

C- Lactose intolerance

D- Ulcerative colitis

The correct answer is A. Celiac disease is a chronic disorder caused by immune reaction to gluten which is found in some foods such as wheat, rye and barley. Symptoms include diarrhea, abdominal pain, weakness, and fatigue. Anti-tissue transglutaminase antibody is diagnostic, but biopsy is needed to confirm it.

Q- Primary osteoporosis generally occurs in which one of the following conditions?

A- Glucocorticoid use

B- Hyperthyroidism

C- Hypogonadism

D- Post-menopause

The correct answer is D. Post-menopause is the only condition on the list that is considered primary. Other conditions lead to secondary osteoporosis.

Q- Which one of the following actions is affected by upregulation and downregulation of the drug receptors?

A- Adaptation to the drug

B- Drug association to the receptor

C- Drug dissociation from the receptor

D- Receptor coupling

The correct answer is A. Adaptation to medication such as tachyphylaxis, desensitization, tolerance, etc. are affected by receptor upregulation and downregulation.

Repeated USMLE Questions Step 1- Review- 88

Read this Review Book for Step 1

More Repeated USMLE Questions Step 1

Leave a Comment