A Case of Wernicke’s Encephalopathy- Repeated USMLE Question

Q- Foci of hemorrhage and necrosis in which of the following parts of the brain is characteristic of Wernicke’s encephalopathy?

A- Anterior pituitary

B- Basal ganglia

C- Mamillary bodies

D- Posterior pituitary

C- Mamillary bodies- This disease is common in alcoholics and characterized by foci of hemorrhage in mamillary bodies and around ventricular regions of thalamus and hypothalamus.

Q- Gonadotropin-releasing hormone is produced by which of the following nuclei of hypothalamus?

A-Anterior nucleus

B- Arcuate nucleus

C- Dorsomedial nucleus

D- Ventromedial nucleus

B- Arcuate nucleus- It produces dopamine, corticotropin-releasing hormone, GH releasing hormone, thyrotropin-releasing hormone and somatostatin.

Q- Which of the following is the most appropriate treatment for a case of Wernicke’s encephalopathy?

A- Biotin

B- Pyridoxine

C- Riboflavin

D- Thiamine

D- Thiamine- It improves the patient’s condition in almost all cases. It is preferred to be administered parenterally as oral absorption is unreliable in these patients.

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2 thoughts on “A Case of Wernicke’s Encephalopathy- Repeated USMLE Question”

  1. Thank you Dr. Abdullah

  2. For joining

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