Repeated USMLE Questions Step 1 Review- 132- Pharmacology

Q- Topical benzocaine overuse can cause sudden cyanosis with normal PaO₂. Which one of the following substances can reverse this reaction? A- Atropine B- Methylene blue C- Naloxone D- Sodium bicarbonate   Q- A 32-year-old woman with a history of migraines is prescribed sumatriptan. What is its mechanism of action? A- 5-HT1B/1D receptor agonist B- … Read more

Repeated USMLE Questions Step 1 Review- 131- Pharmacology

Q- A 64-year-old man with atrial fibrillation is started on warfarin therapy. After 3 days, he develops skin necrosis. Which of the following best explains this complication? A- Direct inhibition of thrombin B- Immediate depletion of clotting factors II, VII, IX, X C- Rapid decline in protein C leading to transient hypercoagulability D- Vitamin K … Read more

Repeated USMLE Questions Step 1 Review- 129- Pharmacology

Q- Which of the following best describes the mechanism of action of carvedilol in treating high blood pressure? A- Calcium channel blocker in vascular smooth muscle B- Central α₂-adrenergic stimulation C- Nonselective β-adrenergic blockade with α₁-adrenergic blockade D- Selective β₁-adrenergic blockade only   Q- Which of the following best describes the mechanism of action of … Read more

Repeated USMLE Questions Step 1 Review- 128- Pharmacology

Q- A patient with hypertension and gout needs a prescription for a diuretic. Which one of the following drugs should be avoided? A- Amiloride B- Furosemide C- Hydrochlorothiazide D- Spironolactone   Q- Which of the following antibiotics is most likely to cause pseudomembranous colitis due to Clostridium difficile? A- Ampicillin B- Ciprofloxacin C- Clindamycin D- … Read more

Repeated USMLE Questions Step 1 Review- 126- Pharmacology

  Q- Which one of the following diuretics is appropriate to be prescribed for hypertension to a patient with a history of calcium oxalate renal stones? A- Acetazolamide B- Furosemide C- Hydrochlorothiazide D- Spironolactone   Q- ACE inhibitors commonly cause a persistent cough. What is most likely the reason for this side effect? A- They … Read more

Repeated USMLE Questions Step 1 Review- 125- Pharmacology

  Q- Which of the following sympathomimetic drugs is the most effective in treating chronic orthostatic hypotension? A- Ephedrine B- Epinephrine C- Norepinephrine D- Salmeterol   Q- Which of the following is the mechanism of action of methotrexate? A- Alkylates DNA B- Blocks topoisomerase II C- Inhibits dihydrofolate reductase D- Inhibits thymidylate synthase   Q- … Read more