Repeated USMLE Questions- Pharmacology- 273

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Q- A certain drug has a high serum protein binding. Which of the following is increased as a result of injecting this drug?

A- Distribution of the drug

B- Drug interaction

C- Liver metabolism

D- Renal excretion

B- Drug interaction- Distribution of the drug to tissue, liver and kidney will decrease while drug interaction with other drug receptors’ protein will increase resulting in drug interaction.



Q- Administration of spironolactone and furosemide leads to which of the following?

A- Increase potassium loss

B- Reduce magnesium loss

C- Reduce potassium loss

D- Reduce sodium loss

C- Reduce potassium loss- Spironolactone is a K-sparing diuretic which will reduce K loss effect of thiazide diuretics. 



Q- Which of the following benefits is achieved as a result of adding progesterone to estrogen in HRT?

A- Decrease bone resorption

B- Decrease the effect of estrogen on the breast

C- Decrease the occurrence of endometrial cancer

D- Increase the effect of estrogen on the heart

C- Decrease the occurrence of endometrial cancer



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6 thoughts on “Repeated USMLE Questions- Pharmacology- 273”

  1. Thank you so much Dr. Haile

  3. Thank you so much

  5. Thank you. I wish you the best of luck in your examinations.

  6. Very useful information
    Thanku

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