Pharmacology MCQs- 300

Q- Which one of the following is the main mechanism of absorption of most drugs in the gastrointestinal tract (GIT)?

A- Endocytosis and exocytosis

B- Facilitated transport

C- Passive diffusion

D- Pinocytosis

C- Passive diffusion- It is explained by Fick Law of Diffusion in which the molecules move from higher drug conc. to lower drug conc.

Q- Which one of the following agents prolongs the duration of nerve block when combined with a local anesthetic?

A- Atropine

B- Dobutamine

C- Epinephrine

D- Isoproterenol

C- Epinephrine- It leads to local vasoconstriction which prolongs the duration of infiltration of nerve block.

Q- Gingival hyperplasia, granulocytopenia and facial hirsutism are possible side effects of which one of the following medications?

A- Carbamazepine

B- Phenobarbital

C- Phenytoin

D- Valproic acid

C- Phenytoin- It may cause gastrointestinal irritation as well.