Repeated USMLE Questions Step 1- Review- 109

Q- An alcoholic man complains of numerous episodes of prolonged vomiting followed by hematemesis during the past two weeks. Vital signs are within normal limits and physical examination is unremarkable. Which of the following is the most likely diagnosis?

A- Barrott esophagus

B- Esophageal cancer

C- Esophageal stricture

D- Mallory-Weiss syndrome

D- Mallory-Weiss syndrome- This condition is characterized by tears in the lining of the esophagus, often caused by severe or prolonged vomiting. It is commonly seen in individuals with a history of heavy alcohol use.

Q- A patient presents for the treatment of peptic ulcer. Which one of the following medications is an H2-receptor antagonist that inhibits histamine-induced gastric acid secretions?

A- Famotidine

B- Omeprazole

C- Prochlorperazine

D- Sucralfate

A- Famotidine- It blocks histamine receptors in the stomach, which reduces the amount of acid the stomach produces. This helps treat and prevent peptic ulcers.

Q- Which of the following is the most frequent form of pericarditis associated with malignancy?

A- Fibrinous pericarditis

B- Hemorrhagic pericarditis

C- Serous pericarditis

D- Suppurative pericarditis

B- Hemorrhagic pericarditis- It is most frequently associated with malignancy. It involves bleeding into the pericardial sac and is often seen in patients with metastatic cancer affecting the pericardium. Hemorrhagic pericarditis also occurs in some cases of tuberculosis.

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