Repeated USMLE Questions Step 1- Review- 120

Q- A 70-year-old man with atrial fibrillation is prescribed warfarin. He is advised to avoid consuming large amounts of leafy green vegetables.

What is the reason for this recommendation?

A- They decrease the anticoagulant effect

B- They increase bleeding risk

C. They increase liver enzyme activity

D. They reduce drug absorption

A- They decrease the anticoagulant effect- Leafy greens are high in vitamin K, which counteracts warfarin’s anticoagulant effect by promoting clotting factor synthesis.

 

Q- A 28-year-old woman is prescribed tetracycline for acne. Which of the following is an important counseling point?

A- Avoid dairy products while taking the medication

B- Do not take with acetaminophen

C- May cause hyperpigmentation of the skin

D- Take with a high-fat meal to enhance absorption

A- Avoid dairy products while taking the medication- Calcium in dairy binds tetracyclines, reducing absorption in the GI tract
.

 

Q- A 62-year-old woman is prescribed nitroglycerin for chronic stable angina. She reports persistent headaches and flushing after use. What is the most likely mechanism behind these side effects?

A- Acetylcholine-induced vasodilation

B- Beta-adrenergic stimulation

C- Increased sympathetic outflow

D- Nitric oxide-mediated vasodilation

D- Nitric oxide-mediated vasodilation- Nitroglycerin is a nitrate that releases nitric oxide, causing vascular smooth muscle relaxation, which leads to headache and flushing.

 

More Pharmacology MCQs

Check this Review Book for USMLE Step 1

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