Q- A 65-year-old man presents with progressive shortness of breath and swelling of his legs. Autopsy shows a heart that is firm and rubbery with amyloid deposition between myocardial fibers.
Which of the following best describes the staining characteristics of amyloid?
A- Congo red positive, apple-green birefringence under polarized light
B- Periodic acid-Schiff positive, resistant to diastase
C- Oil Red O positive, indicating lipid material
D- Prussian blue positive, indicating iron deposition
Q- A 45-year-old woman presents with fatigue and mild hepatosplenomegaly. Peripheral smear reveals teardrop-shaped red cells (dacrocytes) and nucleated RBCs. Bone marrow biopsy is “dry tap.”
What is the most likely diagnosis?
A- Aplastic anemia
B- Myelofibrosis
C- Chronic myeloid leukemia
D- Megaloblastic anemia
Q- A 23-year-old college student presents with fever, sore throat, and lymphadenopathy. Peripheral smear shows atypical lymphocytes with abundant basophilic cytoplasm.
Which of the following is the most likely causative agent?
A- Cytomegalovirus
B- Adenovirus
C- Epstein-Barr virus
D- Streptococcus pyogenes