Q- A 48-year-old man presents with jaundice, dark urine, and pale stools. Lab tests show elevated direct bilirubin and markedly elevated alkaline phosphatase. Ultrasound reveals dilation of intrahepatic bile ducts.
What is the most likely cause?
A-Gilbert disease
B-Hemolytic anemia
C-Obstruction of the common bile duct
D-Viral hepatitis
Q- A 22-year-old man presents with a sudden onset of severe chest pain. Imaging reveals a spontaneous pneumothorax. Lung biopsy shows rupture of small subpleural blebs.
Which condition is most commonly associated?
A-Asthma
B-Chronic smoking history
C-Pulmonary fibrosis
D-Tall, thin body habitus
Q- A 70-year-old man presents with worsening bone pain. His alkaline phosphatase is markedly elevated, but calcium and phosphate levels are normal. X-ray shows thickened cortical bone with a mosaic pattern.
What is the most likely diagnosis?
A-Hyperparathyroidism
B-Osteomalacia
C-Osteoporosis
D-Paget disease of bone