Q- Which one of the following enzymes is most likely deficient in a case of McArdle disease (type V of glycogen storage diseases)?
A- α-1,4- glucosidase
B-Debranching enzyme
C-Glucose-6-phasphatase
D-Myophosphorylase
D-Myophosphorylase- It is skeletal muscle glycogen phosphorylase. Its deficiency leads to accumulation of glycogen in muscles. 3M, McArdle, Myophosphorylase and Muscle. Blood glucose level is not affected.
Q- Which one of the following organisms is the leading cause of urinary tract infections (UTI)?
A-Enterococcus
B-Escherichia coli
C-Proteus mirabilis
D-Pseudomonas aeruginosa
B-Escherichia coli- E coli is the leading cause of UTI. Nitrite test is positive (reduction of urinary nitrates).
Q- Paradoxical splitting of heart sounds can be heard in which one of the following cardiac conditions?
A-Aortic stenosis
B-Atrial septal defect
C-Pulmonary stenosis
D-Right bundle branch block
A-Aortic stenosis- P2 sound occurs before delayed A2 sound so, it reversed the normal order of valve closure. Wide splitting occurs in pulmonary stenosis and RBBB while fixed splitting occurs in ASD.
