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Repeated USMLE Questions Step 1- Pharmacology- 306

Q- A researcher is using a certain drug to experiment its effect to improve hypotension during surgical procedures. This drug is a ganglionic blocker, non-selective, non-competitive nicotinic antagonist. Which of the following drugs is the one used by this researcher?

A-Lisinopril

B-Mecamylamine

C-Methylphenidate

D-Verapamil

B-Mecamylamine-This is the only one on the list that is a ganglionic blocker. It was used on the past as anti-hypertensive drug but it is now used only on research due to its many side effects.



Q- Which of the following medications is helpful to relieve symptoms in a case of chronic heartburn?

A-Cimetidine

B-Milk of magnesium

C-Omeprazole

D-Promethazine

C-Omeprazole- This medication is an irreversible inhibitor of H/K/ATPase so, it reduces gastric acid secretion. It is used in the treatment of GERD, peptic ulcer and Zollinger-Ellison syndrome.



Q- In liver failure, which one of the following medications is used to avoid phase 1 metabolism?

A-Buprenorphine

B-Diazepam

C-Imipramine

D-Lorazepam

D-Lorazepam- This medication and oxazepam are the only benzodiazepines that undergo only phase II metabolism. Other listed drugs undergo first pass metabolism.



More Pharmacology MCQs

Read The Topics on First Aid USMLE Step 1 

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