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Repeated USMLE Questions Step 1- Review- 41- Pharmacology

Q- In a peptic ulcer patient, which one of the following medications acts through reversible block of histamine H2-receptors?

A-Misoprostol

B-Omeprazole

C-Ranitidine

D-Sucralfate

C-Ranitidine- It is the only one on the list that is histamine H2-blocker. Misoprostol is a PGE1 analog. Omeprazole is H/K ATPase inhibitor and Sucralfate binds to ulcer to provide physical protection. This is a very important topic in USMLE.

 

Q- Which one of the following anti-coagulant medications may cause drug-induced thrombocytopenia?

A-Bivalirudin

B-Heparin

C-Streptokinase

D-Warfarin

B-Heparin- DIT is caused by development of IgG antibodies against heparin forming a complex that activates platelets leading to thrombosis and thrombocytopenia.

 

Q- Which one of the following medications is used to prevent cardiotoxicity caused by doxorubicin chemotherapy?

A-Dexrazoxane

B-Leucovorin

C-Mensa

D-Topotecan

A-Dexrazoxane- It is an iron chelating agent used to prevent dilated cardiomyopathy caused by doxorubicin.

 

More Pharmacology MCQs

More USMLE Step 1 Questions 

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