Repeated USMLE Questions Step 1- Review- 72

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Q- Waterhouse-Friderichsen syndrome is characterized by which of the following conditions?

A- Abdominal pain, diarrhea and leukocytosis

B- Adrenal insufficiency, hypotension and disseminated intravascular coagulation

C- Back pain, fever and night sweats

D- Chest pain, pericardial effusion and persistent fever

B- Adrenal insufficiency, hypotension and disseminated intravascular coagulation- Bacterial infection with some organisms such as Neisseria meningitides can lead to sepsis and massive bleeding into one or both adrenal glands. Hypotension and multiple organ failures may follow.   



Q- 1-α-Hydroxylase activity is increased in which of the following conditions?

A- Hypocalcemia and hypophosphatemia

B- Hypoglycemia and ketonuria

C- Hypercalcemia and hyperphosphatemia

D- Hyperglycemia and acidosis

A- Hypocalcemia and hypophosphatemia- 1-α-Hydroxylase is located at the proximal tubule, skin, immune cells and bone. It catalyzes the hydroxylation of calcifediol into calcitriol which is the bioactive form of vitamin D.



Q- Which one of the following tests is highly diagnostic of systemic lupus erythematosus (SLE)?

A-Anti-citrullinated protein antibodies

B- Anti-double stranded DNA (Anti-dsDNA)

C- Anti-RNP antibodies

D- Anti-SSA/Ro autoantibodies

B- Anti-double stranded DNA (Anti-dsDNA)- This is the only test on the list that is highly specific to systemic lupus erythematosus.



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4 thoughts on “Repeated USMLE Questions Step 1- Review- 72”

  1. I agree and thank you for understanding. I don’t really have a pdf of these questions. I just write questions whenever I have time.
    Thanks Dr. Isaac

  2. Thank you Dr Ray. for me pdf its not important. please continue mcqs with answers leave these requesting pdf because pdf we can get everywhere
    Thank you again

  3. I don’t really have a pdf of it. I just post questions on this site. Thank you Dr. Abdifatah for vesting.

  4. This book is very importan one plse can i get pdf form

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