Repeated USMLE Questions Step 1- Review- 152

Q- A 65-year-old man with heart failure is started on spironolactone. Which adverse effect should be monitored most closely? A- Gynecomastia B- Hypocalcemia C- Hypokalemia D- Metabolic acidosis   Q- A 60-year-old man presents with weakness, fatigue, and splenomegaly. His complete blood count shows pancytopenia. Bone marrow aspiration is “dry,” but biopsy shows fibrotic marrow … Read more

Repeated USMLE Questions Step 1 Review-151- Pharmacology

Q- A patient treated for latent tuberculosis develops elevated liver enzymes. Which drug is most likely responsible? A- Cycloserine B- Ethambutol C- Isoniazid D- Streptomycin   Q- A 55-year-old woman with osteoporosis is prescribed a bisphosphonate. Which instruction is most important to prevent esophageal irritation? A- Remain upright for 30 minutes after ingestion B- Take … Read more

Repeated USMLE Questions Step 1 Review-150- Pathology

Q- A 52-year-old man presents with chronic cough, hemoptysis, and digital clubbing. Chest X-ray reveals a coin lesion in the lung. Biopsy shows malignant glandular structures producing mucin. What is the most likely diagnosis? A- Adenocarcinoma B- Large cell carcinoma C- Small cell carcinoma D- Squamous cell carcinoma   Q- A 36-year-old woman presents with … Read more

Repeated USMLE Questions Step 1 Review-149- Pharmacology

Q- A 25-year-old woman is taking oral contraceptive pills (OCPs). Which antibiotic can decrease the effectiveness of her contraceptive therapy? A- Amoxicillin B- Azithromycin C- Ciprofloxacin D- Rifampin   Q- A 60-year-old man with benign prostatic hyperplasia (BPH) and hypertension is prescribed terazosin. Which of the following adverse effects should he be warned about? A- … Read more

Repeated USMLE Questions Step 1 Review-148- Pharmacology

Q- A 32-year-old man presents with dry mouth, blurred vision, and urinary retention after taking an over-the-counter cold medication. Which component is most likely responsible for these symptoms? A- Dextromethorphan B- Diphenhydramine C- Guaifenesin D- Phenylephrine   Q- A 45-year-old woman treated with methimazole for hyperthyroidism develops fever and sore throat. What is the most … Read more

Repeated USMLE Questions Step 1- Review- 147

Q- A 3-year-old boy has recurrent infections, thrombocytopenia, and eczema. Labs show prolonged bleeding time and low IgM. Which mutation is most likely responsible? A-Adenosine deaminase deficiency B-Bruton tyrosine kinase mutation C-CD18 gene defect D-WASP gene mutation   Q- A newborn has a continuous machinery-like murmur. What embryologic structure failed to close? A-Bulbus cordis B-Ductus … Read more