Repeated USMLE Questions Step 1- 305

A week old female presents for her first checkup. Examination reveals jaundice and splenomegaly. Laboratory investigations show: Total bilirubin level: 27 mg/dL Direct bilirubin: 0.6 mg/dL Hgb: 10.1 g/dL Reticulocytes: 6% A blood smear shows burr cells and spherocytosis. Which of these tests will be positive in this patient? A-Acid hemolysis test B-Coomb’s test C-Osmotic … Read more

Repeated USMLE Questions Step 1- 304

A 32-year-old man with a history of HIV infection presents to the clinic complaining of fecal urgency and bloody diarrhea. The patient was diagnosed with pneumocystis jiroveci pneumonia 6 months ago. Which of these organisms is the most likely involved in this condition? A-Clostridium difficile B-cytomegalovirus C-Entamoeba histolytica D-Giardia lamblia Answer Fecal urgency and bloody … Read more

Pharmacology MCQs- 226

A 62-year-old man who has a history of various drug overdose incidents presents to the emergency room after administration of a high dose of aspirin. Which set of these findings characterizes this condition? A-Metabolic acidosis and respiratory acidosis B-Metabolic acidosis and respiratory alkalosis C-Metabolic alkalosis and respiratory acidosis D-Metabolic alkalosis and respiratory alkalosis Answer Salicylate … Read more

Repeated USMLE Questions Step 1- 303

A 1-year-old girl is brought to the pediatrician by her parents due to poor growth and skeletal abnormalities. Laboratory investigations show microcytic anemia and higher concentration of hemoglobin A2. Which is the most likely diagnosis? A- Sickle cell anemia B- β-thalassemia C- Lead poisoning D- Iron deficiency Answer β-thalassemia is an inherited blood disorder that … Read more

Repeated USMLE Questions Step 1-302

A 60-year-old man visits the clinic due to profuse watery diarrhea and left lower abdominal colicky pain for the last 6 hours. Upon taking history, the patient claims that he is taking broad spectrum antibiotics for acute bronchitis. Which is the most likely causative organism for the patient’s new symptoms? A- Clostridium botulinum B- Clostridium … Read more

Repeated USMLE Questions Step 1- 301

A 52-year-old man who is recently diagnosed with gout is presented to his physician to discuss his treatment plan. One of the treatments that will be taken is allopurinol. Which of these enzymes is targeted by this medication? A-Hypoxanthine guanine phosphoribosyltransferase B-Phosphoribosylpyrophosphate synthase C-Guanase D-Xanthine oxidase Answer Allopurinol is used to treat chronic gout due … Read more