Repeated USMLE Questions Step 1- 268

A 19-year-old man presents to the clinic with a complaint of tremors and incoordination. Serum transaminases are slightly elevated. Slit lamp examination shows brownish corneal deposits. What is the element directly involved in this condition? A-Arsenic B-Lead C-Copper D-Iron E-Zinc Answer This is a presentation of Wilson’s disease in which cellular copper transport is disturbed … Read more

Repeated USMLE Questions Step 2 CK- 422

A 22-year-old G2P1 at 28 weeks gestation presents to the emergency room with heavy vaginal bleeding. Which of the following is NOT recommended as the next step of action? A- Admit the patient B- Digital pelvic examination C- Stabilize the patient D- Ultrasound examination of the pelvis Answer Digital pelvic examination is contraindicated unless the … Read more

Medical Question of the Day- 33

Workers in the aniline dye industry are more susceptible to bladder cancer than general population. Meanwhile, studies show that animals, when exposed to beta-naphthylamine develop liver cancer but not bladder cancer. What is the most likely explanation of this finding? A-Metabolism of beta-naphthylamine by human cytochrome 450 system in the liver B-Detoxification of beta-naphthylamine by … Read more

Repeated USMLE Questions Step 1- 266

A 12-year-old girl visits her physician for follow up after treatment with methotrexate for acute lymphoblastic leukemia. Stool analysis reveals blood in stool. Her platelet count is very low. Which of these substances should be administered immediately? A-Vitamin K B-Leucovorin C-Deferoxamine D-Amitriptyline E-Penicillamine Answer This is a case of methotrexate toxicity. Leucovorin is the active … Read more

Repeated USMLE Questions Step 2 CK- 421

A 48-year-old man with a long history of type 1 diabetes and hypertension develops sudden chest pain and dizziness. On examination, pulse is 110, blood pressure is 80/50, no pulsus paradoxus, lungs are clear and jugular veins are dilated. ECG shows sinus tachycardia with ST elevation in leads II, III and AVF. What is the … Read more