Repeated USMLE Questions Step 1- 268



A 19-year-old man presents to the clinic with a complaint of tremors and incoordination. Serum transaminases are slightly elevated. Slit lamp examination shows brownish corneal deposits.

What is the element directly involved in this condition?

A-Arsenic

B-Lead

C-Copper

D-Iron

E-Zinc

Answer



This is a presentation of Wilson’s disease in which cellular copper transport is disturbed resulting in copper deposition on tissues. Deposition of copper on the cornea leads to Kayser-Fleischer ring which is found in this patient.

The correct answer is C



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