Repeated USMLE Questions Step 1 Review-178- Pathology

Q- A 45-year-old man presents with epigastric pain that improves with eating. Endoscopy reveals a duodenal ulcer.
Which organism is most commonly responsible for this condition?

A- Campylobacter jejuni

B- Clostridioides difficile

C- Helicobacter pylori

D- Vibrio cholerae

C- Helicobacter pylori- H. pylori infection causes chronic gastritis and increases risk for duodenal ulcers, gastric adenocarcinoma, and MALT lymphoma.

 

Q- A 70-year-old man presents with progressive difficulty initiating urination and a weak urinary stream. Biopsy reveals nodular enlargement of the periurethral prostate glands.
What is the most likely diagnosis?

A- Benign prostatic hyperplasia

B- Prostate adenocarcinoma

C- Prostatic intraepithelial neoplasia

D- Prostatitis

A- Benign prostatic hyperplasia- BPH results from androgen-driven hyperplasia of periurethral glands, causing urinary obstruction in older men.

 

Q- A 32-year-old woman presents with fatigue and dark urine. Laboratory studies show anemia, elevated LDH, and decreased haptoglobin. A direct Coombs test is positive.
What is the most likely diagnosis?

A- Autoimmune hemolytic anemia

B- Glucose-6-phosphate dehydrogenase deficiency

C- Hereditary spherocytosis

D- Sickle cell disease

A- Autoimmune hemolytic anemia- A positive direct Coombs test indicates antibodies directed against RBCs, causing autoimmune hemolytic anemia with extravascular hemolysis.

 

Read this Pathology MCQs Book

More Repeated USMLE Questions Step 1

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Dr Ray Makar

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