Repeated USMLE Questions Step 1 Review- 130- Pathology

Q- A 55-year-old man with a long history of alcohol use presents with abdominal distension. Physical exam reveals shifting dullness and spider angiomas on the chest. His lab results are: total bilirubin 3.2 mg/dL, albumin 2.1 g/dL, and an INR of 1.9. Which of the following best explains the pathophysiology of his condition? A- Autoimmune … Read more

Repeated USMLE Questions Step 1 Review- 129- Pharmacology

Q- Which of the following best describes the mechanism of action of carvedilol in treating high blood pressure? A- Calcium channel blocker in vascular smooth muscle B- Central α₂-adrenergic stimulation C- Nonselective β-adrenergic blockade with α₁-adrenergic blockade D- Selective β₁-adrenergic blockade only   Q- Which of the following best describes the mechanism of action of … Read more

Repeated USMLE Questions Step 1 Review- 128- Pharmacology

Q- A patient with hypertension and gout needs a prescription for a diuretic. Which one of the following drugs should be avoided? A- Amiloride B- Furosemide C- Hydrochlorothiazide D- Spironolactone   Q- Which of the following antibiotics is most likely to cause pseudomembranous colitis due to Clostridium difficile? A- Ampicillin B- Ciprofloxacin C- Clindamycin D- … Read more

Repeated USMLE Questions Step 1 Review- 127- Pathology

Q- Which one of the following laboratory tests can differentiate primary aldosteronism from secondary aldosteronism? A- Plasma aldosterone concentration B- Plasma renin activity C- Serum cortisol D- Serum sodium   Q- Which one of the following is the most frequent form of pericarditis associated with myocardial infarction? A- Constrictive pericarditis B- Fibrinous pericarditis C- Hemorrhagic … Read more

Repeated USMLE Questions Step 1 Review- 126- Pharmacology

  Q- Which one of the following diuretics is appropriate to be prescribed for hypertension to a patient with a history of calcium oxalate renal stones? A- Acetazolamide B- Furosemide C- Hydrochlorothiazide D- Spironolactone   Q- ACE inhibitors commonly cause a persistent cough. What is most likely the reason for this side effect? A- They … Read more

Repeated USMLE Questions Step 1 Review- 125- Pharmacology

  Q- Which of the following sympathomimetic drugs is the most effective in treating chronic orthostatic hypotension? A- Ephedrine B- Epinephrine C- Norepinephrine D- Salmeterol   Q- Which of the following is the mechanism of action of methotrexate? A- Alkylates DNA B- Blocks topoisomerase II C- Inhibits dihydrofolate reductase D- Inhibits thymidylate synthase   Q- … Read more