Repeated USMLE Questions Step 1 Review- 139- Pathology

Q- A 65-year-old man presents with progressive shortness of breath and swelling of his legs. Autopsy shows a heart that is firm and rubbery with amyloid deposition between myocardial fibers. Which of the following best describes the staining characteristics of amyloid? A- Congo red positive, apple-green birefringence under polarized light B- Periodic acid-Schiff positive, resistant … Read more

Repeated USMLE Questions Step 1 Review- 138- Pharmacology

Q- A 60-year-old patient with chronic heart failure is started on digoxin. Which electrolyte imbalance increases the risk of digoxin toxicity? A- Hyperkalemia B- Hypocalcemia C- Hypokalemia D- Hyponatremia   Q- Which of the following drugs inhibits bacterial folate synthesis by blocking dihydropteroate synthase? A- Ciprofloxacin B- Isoniazid C- Trimethoprim D- Sulfamethoxazole   Q- A … Read more

Repeated USMLE Questions Step 1 Review- 137- Pathology

Q- A 60-year-old woman presents with progressive jaundice and weight loss. Imaging shows a mass at the head of the pancreas. Which of the following is the most likely paraneoplastic finding? A- Cushing syndrome B- Hypercalcemia due to PTHrP secretion C- Hyponatremia due to SIADH D- Migratory thrombophlebitis (Trousseau syndrome)   Q- A 27-year-old man … Read more

Repeated USMLE Questions Step 1 Review- 136- Pharmacology

Q- Which of the following drugs is a reversible cholinesterase inhibitor used in the management of myasthenia gravis? A- Atropine B- Neostigmine C- Pralidoxime D- Succinylcholine   Q- A patient with atrial fibrillation is prescribed warfarin. Which of the following factors will increase the anticoagulant effect of warfarin? A- Vitamin K deficiency B- Rifampin therapy … Read more

Repeated USMLE Questions Step 1 Review- 135- Pathology

Q- A 62-year-old man with a history of chronic alcohol use presents with weight loss, epigastric pain, and jaundice. CT scan shows a mass in the head of pancreas. Which tumor marker is most useful for this diagnosis? A- Alpha-fetoprotein (AFP) B- Cancer antigen 19-9 (CA 19-9) C- Carcinoembryonic antigen (CEA) D- Prostate-specific antigen (PSA) … Read more

Repeated USMLE Questions Step 1 Review- 134- Pharmacology

Q- A 25-year-old man is treated with chloramphenicol for typhoid fever. He later develops pallor, fatigue, and pancytopenia. Which adverse effect best explains this presentation? A- Dose-dependent reversible anemia B- Folate deficiency C- Irreversible aplastic anemia D- Vitamin B12 deficiency   Q- A 60-year-old woman with hypertension is prescribed hydralazine. Which adverse effect is most … Read more