Repeated USMLE Questions Step 1- 254

A 4-year old girl is brought to the clinic by her mother complaining of fever and abdominal pain since yesterday. Today, she looks uncomfortable during micturition. On examination, her temperature is 99.4, her pulse is 100/min. and her suprapubic area is soft and tender. Her blood analysis shows increased neutrophils. Her urinalysis is positive for organisms and leukocytes.

What is the drug of choice for this condition?

A- Ciprofloxacin

B- Chloramphenicol

C- C0-trimoxazole

D- Rifampin


This is a case of bacterial urinary tract infection. E-Coli is the most common organism associated with this condition. The drug of choice is co-trimoxazole. It is safe to use at his age.

Ciprofloxacin is indicated in complicated cases of urinary tract infections. It is not recommended as the first line of treatment due to its side effects. Chloramphenicol and rifampin are not recommended for this age nor this condition.

The correct answer is C

7 thoughts on “Repeated USMLE Questions Step 1- 254”

  1. The case has not hinted whether our patient is allergic to sulphur,this is a dangerous assumption if Steven-Johnson’s disease is to be considered.

  2. Did you read the explanation Dr Ali?

  3. l need some light that c is an answer

  4. You’re welcome Dr.

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