Repeated USMLE Questions Step 1- Review- 63- Pharmacology

Q- Which one of the following medications is beneficial in osteoporosis and acts by inhibition of osteoclastic activity more than osteoblastic activity?

A- Alendronate

B- Calcitonin

C- Calcium gluconate

D- Vitamin D

A- Alendronate- It is beneficial also in cases of hypercalcemia of malignancy and Paget disease. Other medications have different mechanisms of action.

Q- In a patient diagnosed with carcinoid tumor, which of the following conditions is manifested due to high level of serotonin?

A- Constipation

B- Diarrhea

C- Skeletal muscle weakness

D- Tachycardia

B- Diarrhea- Serotonin receptors mediate smooth muscle contraction which leads to diarrhea and bronchospasm. It doesn’t affect skeletal or cardiac muscle as they are insensitive to serotonin.

Q- A 28-year-old man has been treated for bipolar disorder with lithium carbonate. Which of the following is a common side effect of this drug?

A- Dry mouth

B- Hyperthyroidism

C- Nephrogenic diabetes insipidus

D- Parkinsonism

C- Nephrogenic diabetes insipidus- It is a common side effect of lithium beside hypothyroidism, not hyperthyroidism and tremor, not parkinsonism.

More Pharmacology MCQs

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