Repeated USMLE Questions Step 1 Review- 142- Pharmacology

Q- A 55-year-old man with atrial fibrillation is taking warfarin. He is started on trimethoprim-sulfamethoxazole for a urinary tract infection. What is the most likely outcome of this drug interaction? A- Decreased anticoagulant effect B- Enhanced metabolism of warfarin C- Increased risk of bleeding D- No significant effect   Q- A 35-year-old woman with generalized … Read more

Repeated USMLE Questions Step 1 Review- 141- Pathology

Q- A 48-year-old man presents with jaundice, dark urine, and pale stools. Lab tests show elevated direct bilirubin and markedly elevated alkaline phosphatase. Ultrasound reveals dilation of intrahepatic bile ducts. What is the most likely cause? A-Gilbert disease B-Hemolytic anemia C-Obstruction of the common bile duct D-Viral hepatitis   Q- A 22-year-old man presents with … Read more

Repeated USMLE Questions Step 2 CK- Review- 44

Q- A 68-year-old woman presents with a sudden onset of chest pain that radiates to her back. Blood pressure is 190/100 mmHg. She has a history of long-standing hypertension. CT angiography shows a tear in the intimal layer of the aorta. Which of the following is the most appropriate initial treatment? A- Give aspirin B- … Read more

Repeated USMLE Questions Step 1 Review- 140- Pharmacology

Q- A 60-year-old man with atrial fibrillation is started on amiodarone. Which adverse effect is most commonly associated with this medication? A- Hyperkalemia B- Hypoglycemia C- Nephrotoxicity D- Pulmonary fibrosis   Q- A 28-year-old woman develops a dry cough after beginning treatment for hypertension. Which drug is most likely responsible? A- Amlodipine B- Lisinopril C- … Read more

Repeated USMLE Questions Step 1 Review- 139- Pathology

Q- A 65-year-old man presents with progressive shortness of breath and swelling of his legs. Autopsy shows a heart that is firm and rubbery with amyloid deposition between myocardial fibers. Which of the following best describes the staining characteristics of amyloid? A- Congo red positive, apple-green birefringence under polarized light B- Periodic acid-Schiff positive, resistant … Read more

Repeated USMLE Questions Step 1 Review- 138- Pharmacology

Q- A 60-year-old patient with chronic heart failure is started on digoxin. Which electrolyte imbalance increases the risk of digoxin toxicity? A- Hyperkalemia B- Hypocalcemia C- Hypokalemia D- Hyponatremia   Q- Which of the following drugs inhibits bacterial folate synthesis by blocking dihydropteroate synthase? A- Ciprofloxacin B- Isoniazid C- Trimethoprim D- Sulfamethoxazole   Q- A … Read more