pharmacology

A 24-year-old woman visits her physician for treatment of anxiety. She requests to change her current medication because it is sedative. Which one of these drugs has the minimum sedative effect? A-Buspirone B-Lorazepam C-Midazolam D-Promethazine E-Trazodone Answer Buspirone is non-benzodiazepine anti-anxiety medication and has the minimum sedation effect compared to benzodiazepines such as lorazepam and … Read more

Studies are done on normal volunteers for phase 1 clinical trials of a new drug. The volume of distribution and clearance has been measured. The researchers now are calculating the half-life of the drug. Assuming that the volume of distribution is 60 L and the clearance is 3 L/hour, what is the approximate half-life of … Read more

A 40-year-old man who works in a manufacture of explosives presents to the clinic for a routine physical examination. Medical history reveals that the patient experiences episodes of headache and palpitation every Monday. Physical examination, laboratory tests and ECG show normal results. The patient questions if the chemicals related to his job could be responsible … Read more

A 45-year-old woman is sent to the emergency room from a vision center after examining her eyes to get new glasses. While she was in the waiting room, she developed severe ocular pain in her right eye and she started seeing halos around light. Which of these agents most likely is the reason for this … Read more

A 62-year-old man who has a history of various drug overdose incidents presents to the emergency room after administration of a high dose of aspirin. Which set of these findings characterizes this condition? A-Metabolic acidosis and respiratory acidosis B-Metabolic acidosis and respiratory alkalosis C-Metabolic alkalosis and respiratory acidosis D-Metabolic alkalosis and respiratory alkalosis Answer Salicylate … Read more