Pharmacology MCQs- 285

Q- A 30-year-old man with hypertension is prescribed labetalol. It antagonizes which of the following receptors to be effective against hypertension?

A- Alpha-adrenoceptors

B- Beta-adrenoceptors

C- Both alpha and beta adrenoceptors

D- Nicotinic receptors

C- Both alpha and beta adrenoceptors- Labetalol blocks both of these receptors to lower the blood pressure through decreasing systemic vascular resistance.

Q- Which of the following is the most effective role of probenecid in treating gout?

A- Probenecid decreases inflammation of affected joints

B- Probenecid decreases the production of uric acid

C- Probenecid decreases the reabsorption of uric acid

D- Probenecid decreases the secretion of uric acid

C- Probenecid decreases reabsorption of uric acid- Although probenecid decreases secretion of urate in renal tubules, its most effective action is inhibition of reabsorption of uric acid.

Q- Which of the following is considered a limiting adverse effect of ACE inhibitors?

A- Acidosis

B- Hyperkalemia

C- Hypokalemia

D- Hyponatremia

B- Hyperkalemia- ACE inhibitor intake leads to reduction of aldosterone levels which results in decreased K excretion. Limiting these drugs is considered in cases of hyperkalemia.